Can a MSI GeForce RTX 3080 VENTUS 3X 10G OC run FLUX.1 dev (12B)?

Sort of — Runs with compromises

Too big for 10 GB of VRAM (needs ~13 GB), but it can run by offloading part of the model to system RAM — slower, and it uses your RAM. A smaller quantization may help.

Your VRAM