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Can a Asus STRIX-GTX750TI-DC2OC-4GD5 run Mixtral 8x7B?

Sort of — Runs with compromises

Too big for 4 GB of VRAM (needs ~30 GB), but it can run by offloading part of the model to system RAM — slower, and it uses your RAM. A smaller quantization may help.

Your VRAM
4 GB
Needs (est.)
30 GB
Quantization
Q4_K_M