Can a MSI GeForce RTX 3070 Ventus 3X 8G OC LHR run Qwen2.5 72B?

Not really — Not recommended

Needs ~46 GB and won't fit comfortably in 8 GB VRAM + 32 GB RAM at a usable speed. A larger-VRAM GPU or a smaller model is the way to run this.

Your VRAM