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Can a MSI GeForce RTX 3080 VENTUS 3X 10G OC run Stable Diffusion 3.5 Large?

Yes — Runs well

Fits in 10 GB of VRAM (needs ~10 GB) — runs fully on the GPU at FP8.

Your VRAM
10 GB
Needs (est.)
10 GB
Quantization
FP8